The San Francisco 49ers (12-3) have a chance to win the NFC West and earn home field advantage throughout the postseason on “Sunday Night Football” with a win over the Seattle Seahawks (11-4). San Francisco would have locked up the NFC West last week if the 49ers would have defeated the Atlanta Falcons in Week 15, but the 49ers were upset in that game and would be the No. 5 seed with a loss to Seattle on Sunday night.Seattle could be playing for home field advantage throughout the postseason if Green Bay and New Orleans both lose earlier on Sunday. The Seahawks would win a tiebreaker with those teams to be the No. 1 team in the NFC with a win over the 49ers in that scenario, and they would be playing for a first-round bye if either the Packers or the Saints lost in Week 17. If Green Bay and New Orleans both win though, Seattle could only earn the No. 3 seed in the NFC with a win over San Francisco. Player to watchJimmy Garoppolo was not sharp against the Rams last week. He was sacked six times and threw two interceptions, and that almost led to a San Francisco loss. The 49ers overcame that performance to get a win, but they must protect Garoppolo better on Sunday. Seattle sacked Jimmy G five times in their first meeting, leading to Garoppolo’s worst performance of the season that wasn’t affected by weather.Seahawks vs. 49ers predictionThere are too many questions with Seattle’s running game, so expect San Francisco to take this game over with its defense and run game.49ers 27, Seahawks 20 Here’s everything to know about betting on Seahawks vs. 49ers in Week 17, including updated odds, trends and our prediction for “Sunday Night Football.”MORE: Get the latest NFL odds & betting trends at Sports InsiderSeahawks vs. 49ers odds for ‘Sunday Night Football’Seattle Seahawks +3 vs. San Francisco 49ers, O/U 47San Francisco opened as a two-point favorite in this game on Monday, but a rush of 49ers money quickly moved the line to SF -3. The total has remained steady at 47 throughout the week though.Seahawks vs. 49ers series historyThe Seahawks are 26-16 against the 49ers in their history. These two teams only became divisional foes in 2002 when Seattle moved from the AFC West to the NFC West, and Seattle is 24-12 against San Francisco as members of the same division.Seattle knocked off San Francisco in the NFC Championship Game six years ago on its way to winning Super Bowl XLVIII. Since that point, the Seahawks are 10-1 against the 49ers, and their only loss was in overtime last year in Santa Clara. They avenged that defeat by beating San Francisco in Levi’s Stadium in Week 10, dealing the Niners their first loss of the year.Three trends to know— San Francisco is 7-15-1 ATS in its last 23 games against conference foes.— The 49ers are 6-19-1 ATS the last 26 times they were favored to win a game.— Seattle is 33-15-3 ATS in its last 51 games as an underdog on the betting line.Three things to watchBeast Mode is backSeattle’s top three running backs coming into the season are all on injured reserve. Chris Carson, Rashaad Penny, and C.J. Prosise have all suffered season-ending injuries, so the Seahawks are turning to a familiar face to carry the load. They signed Marshawn Lynch to complement rookie Travis Homer in the backfield, and Lynch is expected to see some action on Sunday night.Lynch was doling out shots of tequila in a parking lot in Oakland two weeks ago, and no one knows whether he is in game shape. He retired at the end of last season after averaging 4.2 YPC in Oakland, so Seattle will likely test his fitness in this game by giving him at least 10 carries.Will Russell Wilson be Dangeruss on Sunday night?Russell Wilson has been fantastic for Seattle this season. Wilson is probably going to finish runner-up to Lamar Jackson in the NFL MVP award voting, completing 66.4 percent of his passes for 3,877 yards with 29 touchdowns and 5 interceptions. He has been a great runner too, averaging 4.7 YPC, and he came up big against San Francisco in the first meeting between these two teams.George Kittle is available this timeKittle has been one of the most underrated players in the NFL this season. He has been the best all-around tight end in the league with his run blocking and pass catching ability, and his presence has been instrumental in making this offense one of the best in the NFC. Kittle didn’t play the first time these teams met, and Seattle will find it hard to stop him.